It is located on the left bank of the Rhône River, opposite Tournon-sur-Rhône, which is located in Ardèche. The view from the vine-covered hill above the town has attracted many tourists, including Thomas Jefferson.
A notable wine producing commune, wines include Hermitage AOC and Crozes-Hermitage AOC, Cornas AOC. The red wines are produced from Syrah, and the whites from Marsanne and/or Roussanne. Tain-l'Hermitage is home to a large number of wineries, including Maison M. Chapoutier, Caves de Tain and Paul Jaboulet Âiné, as well as many smaller domaines.