The island belongs to the Cinque Islands of Rutland Archipelago and is located between North Cinque Island (1.5 km (1 mi) to the north) and Passage Island (6.2 km (4 mi) to the south). The passage between South Cinque and North Cinque is called Cinque Strait. South Cinque Island and North Cinque Island, 1.5 km (1 mi) to the north, are sometimes considered to be a single Cinque Island.
Politically, South Cinque Island is part of Port Blair Taluk.
A new species of blenny, Alloblennius frondiculus was found in the surrounding waters.