There are several named islands within the sound, including: Lock, Vivian, Prescott, Pandora, Otrick, Barth, De la Roquette, and Gibson.
Sir John Franklin passed through the strait in 1846 - an unseasonably warm summer, since typically Peel Sound is frozen. Its east side was traced by James Clark Ross in 1849. In 1858 Francis Leopold McClintock tried to penetrate it and was blocked by ice. The same thing happened to Allen Young in 1875.