It is the smallest municipality in the province, in both area and population. Located at an island of the same name, it lies south of Leyte, in the Mindanao or Bohol Sea. The island, also known as Sarangani Island, is about 10 kilometres long from north to south. This is most famous for the first mass in the Philippines officiated on Easter Sunday of March 31, 1521 by Father Pedro de Valderrama under the fleet of Ferdinand Magellan.
Limasawa is politically subdivided into 6 barangays.